Lung Health and the Exposome - How Environmental Factors Influence Lung Health

This book is ideal for the practicing clinician looking to better understand how our environment impacts the lung. A compilation of reviews explores how clinicians can be aware and better determine environmental effects on lung health, and provides guidelines for medical providers to diagnose, counsel and mitigate risk. Various lung diseases are affected by the external environment. Asthma is common, however other airways diseases, such as interstitial lung disease, malignancies, and even adverse effects from reactions treatments for other medical conditions can affect the health of the lungs. While there are books and chapters written on occupational lung disease and environmental causes of asthma, the intent of this body of work is to address the exposome and the effects on a broader group of lung disease. 
In addition to information on traditional exposure sources, such as air pollution and occupational exposures, this resource explores newer areas of interest, including lung disease from recreational inhalants and the role of climate change on lung health. Written by expert respiratory specialists, the articles cover a wide range of topics, including:

• How air pollution effects airways disease, including asthma, COPD, and cystic fibrosis
• Risk factors and effects of indoor mold exposure
Both medical and non-medical exposures that increase the risk of or cause interstitial lung disease (ILD) also known as diffuse parenchymal lung disease (DPLD)
• Acute and chronic lung disease associated with recreational inhalants
• The epidemiologic and molecular mechanisms of air pollution effects on pulmonary hypertension
• Climate change and weather-related lung health issues
• Areas in this field that need further evaluation

 





Dr. Pennington completed her undergraduate education at Johns Hopkins University.  Following this, she completed her medical school and Internal Medicine residency training at The Ohio State University.  Then she completed her Pulmonary and Critical Care fellowship at Wake Forest Baptist Medical Center.  She joined the Cleveland Clinic Respiratory Institute after fellowship practicing Pulmonary and Critical Care medicine, working in the ICU and in the Asthma Center at Cleveland Clinic.  An assistant professor of medicine at Cleveland Clinic Lerner College of Medicine, her main clinical interest is in asthma, including outcomes research and clinical trials to bring new treatments to asthma patients.  She is active in the NIH Severe Asthma Research Program (SARP) and Precision Interventions for Severe Asthma (PrecISE) Network. She is also active in the American Thoracic Society in the Assembly on Allergy, Inflammation and Immunology.
Dr. Khatri completed her medical education at The Ohio State University College of Medicine, with post graduate training at Loyola University Hospital and  Pulmonary/Critical Care Medicine training at Cleveland Clinic. She is a Professor of Medicine, Director of the Asthma Center, and Vice Chair of the Respiratory Institute at Cleveland Clinic. She co-edited and published the Clinics in Chest Medicine edition of Asthma (March 2019), and is a public health advocate working in partnership with non-profit organizations and the American Thoracic Society, active in clinical trials regarding biologic therapies, and is a research collaborator in the NIH Asthma Research Network.